N-甲基脯氨酸甲酯

N-甲基脯氨酸甲酯是一种有机化合物,化学式为C7H13NO2。它可由脯氨酸甲酯原甲酸三甲酯氢气三氟乙酸及催化剂存在下反应制得。[1]它和氟硼酸反应,可以得到相应的氟硼酸盐。[2]它和碘甲烷反应,可以得到N,N'-二甲基脯氨酸甲酯碘化物。[3]

N-甲基脯氨酸甲酯
别名 1-甲基脯氨酸甲酯
识别
CAS号 933-94-8  checkY
114883-82-8(D)  checkY
27957-91-1(L)  checkY
性质
化学式 C7H13NO2
摩尔质量 143.18 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Kadyrov, Renat; Moebus, Konrad. Reductive Alkylation of Amines with Carboxylic Ortho Esters. Advanced Synthesis & Catalysis, 2020. 362 (16): 3352-3357. doi:10.1002/adsc.202000510.
  2. ^ Kasperowicz-Frankowska, Katarzyna; Gzik, Anna; Dziemidkiewicz, Michal; Kolesinska, Beata; Kaminski, Zbigniew J. Synthesis of chiral triazine coupling reagents based on esters of N-alkylproline and their application in the enantioselective incorporation of D or L amino acid residue directly from racemic substrate. Acta Poloniae Pharmaceutica, 2014. 71 (6): 994-1003. ISSN 2353-5288
  3. ^ Martin, Lisandra L.; Lu, Jinzhen; Nafady, Ayman; Le, Thanh Hai; Siriwardana, Amal I.; Qu, Xiaohu; Traore, Daouda A. K.; Wilce, Matthew; Bond, Alan M. Novel Semiconducting Biomaterials Derived from a Proline Ester and Tetracyanoquinodimethane Identified by Handpicked Selection of Individual Crystals. Australian Journal of Chemistry, 2012. 65 (7): 935-941. doi:10.1071/ch12183.