鼻孢子虫病

鼻孢子虫病(Rhinosporidiosis)又称鼻芽孢虫病,是西氏鼻孢子虫英语Rhinosporidium seeberi感染人类、其他哺乳动物与鸟类所造成的疾病[注 1]。此病最早于1896年由阿根廷医师吉列尔摩·西伯(Guillermo Rodolfo Seeber)在一名病患中发现[3],其病原过去长期被认为属于真菌,近代分子证据才发现其属于中菌动物动物总界基群的类群)[4]

鼻孢子虫病
口腔被鼻孢子虫感染的病患
病因西氏鼻孢子虫英语Rhinosporidium seeberi感染
治疗切除病灶
分类和外部资源
医学专科传染病学
ICD-111F56
ICD-9-CM117.0
DiseasesDB31328
eMedicine227734
[编辑此条目的维基数据]

鼻孢子虫病最常见于南亚南美洲非洲等热带地区,其中印度斯里兰卡的感染率最高[4][5][6][7],且男性感染率高于女性[5]。感染途径可能是于池塘与湖泊中经动物的粪便感染[4]

西氏鼻孢子虫大多感染粘膜,造成如草莓状的息肉[4],其中约七成患者为鼻咽被感染,约15%则为眼睛结膜被感染,其他身体部位的感染也曾被报导。此病常为长期且无痛的感染,极少有造成全身感染而致死的案例[5];其治疗方法一般为切除病灶,有时事后再施以达普颂抗生素以预防患部发生细菌感染[1]

注脚

  1. ^ 另一种鼻孢子虫有感染两生类的纪录[1][2]

参考文献

  1. ^ 1.0 1.1 Mayet, Huzaifah; Reddy, Denasha L.; Alvarez, Tika Bello; Atiya, Yahya; Govender, Nelesh P.; Birkhead, Monica; Maphanga, Tsidiso; Pather, Sugeshnee. Case Report of Nasal Rhinosporidiosis in South Africa. Emerging Infectious Diseases. 2024-04, 30 (4). doi:10.3201/eid3004.240018. 
  2. ^ Scheid, P; Balczun, C; Dehling, Jm; Ammon, A; Sinsch, U. Rhinosporidiosis in African reed frogs Hyperolius spp. caused by a new species of Rhinosporidium. Diseases of Aquatic Organisms. 2015-07-23, 115 (2): 111–120. doi:10.3354/dao02888. 
  3. ^ Mendoza, Leonel; Vilela, Raquel. Anomalous fungal and fungal-like infections: lacaziosis, pythiosis, and rhinosporidiosis. Clinical Mycology. 2009: 403–415. doi:10.1016/B978-1-4160-5680-5.00018-9. 
  4. ^ 4.0 4.1 4.2 4.3 Prakash, M; Johnny, JCarlton. Rhinosporidiosis and the pond. Journal of Pharmacy And Bioallied Sciences. 2015, 7 (5): 59. doi:10.4103/0975-7406.155804. 
  5. ^ 5.0 5.1 5.2 Duane R Hospenthal. Rhinosporidiosis. Medscape. 2023-02-15. 
  6. ^ Berrocal, Alexis; López, Alfonso. Nasal rhinosporidiosis in a mule. The Canadian Veterinary Journal. March 2007, 48 (3): 305–306. PMC 1800950 . PMID 17436910. 
  7. ^ Morelli, Luca; Polce, Mario; Piscioli, Francesco; Del Nonno, Franca; Covello, Renato; Brenna, Alessia; Cione, Antonio; Licci, Stefano. Human nasal rhinosporidiosis: an Italian case report. Diagnostic Pathology. December 2006, 1 (1): 25. PMC 1560165 . PMID 16945122. doi:10.1186/1746-1596-1-25 .