雄二烯酮

化合物

雄二烯酮 (英語:androstadienone), 又稱雄甾二烯酮雄甾-4,16,-二烯-3-酮,是人類男性費洛蒙[1],這種化學物質被描述成對人類具有強烈的費洛蒙相關的作用[2][3][4]。雄二烯酮(費洛蒙酮)是雄性荷爾蒙睪固酮代謝物。然而,雄二烯酮並不會產生任何雄性激素或同化激素的活性作用。雖然研究報告顯示雄二烯酮會明顯地影響異性戀女人與同性戀男人的心情[5],並且很微妙地吸引別人的注意[6],但卻不會明顯地影響人類的行為。雄二烯酮(費洛蒙酮)目前被添加到香水中,據稱能夠增加對異性戀女性與同性戀男性的吸引力[7]

雄二烯酮
臨床資料
ATC碼
  • 未分配
識別資訊
  • (8S,9S,10R,13R,14S)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one
    OR
    (1S,2R,10S,11S,15R)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,13-dien-5-one
CAS號4075-07-4  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C19H26O
摩爾質量270.42 g·mol−1
3D模型(JSmol英語JSmol
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=CC(=O)CC[C@]34C
  • InChI=1S/C19H26O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,12,15-17H,4-8,10-11H2,1-2H3/t15-,16-,17-,18-,19-/m0/s1 checkY
  • Key:HNDHDMOSWUAEAW-VMXHOPILSA-N checkY

相關條目

參見

  1. ^ 周延鑫. 人類的性費洛蒙 - 國家科學委員會. 科學發展. 2008, 421: 48-53. (原始內容存檔於2012-07-24). 
  2. ^ Ivanka Savic,Hans Berglund and Per Lindström. Brain response to putative pheromones in homosexual men. PNAS. 2005, 102 [2011-05-19]. doi:10.1073/pnas.0407998102. (原始內容存檔於2021-05-12). 
  3. ^ Robert Sanders University of California Berkeley. Chemical In Male Sweat Increases Cortisol And Sexual Arousal In Heterosexual Women. medical news today. 2007 [2011-05-19]. (原始內容存檔於2010-01-11). 
  4. ^ Wyart C, Webster WW, Chen JH, Wilson SR, McClary A, Khan RM, Sobel N. 嗅闻人类男性汗水中的单一成分就会改变女性体内的可体松荷尔蒙 Smelling a single component of male sweat alters levels of cortisol in women. J Neurosci. February 2007, 27 (6): 1261–5. PMID 17287500. doi:10.1523/JNEUROSCI.4430-06.2007. 
  5. ^ Jacob S, McClintock MK. Psychological State and Mood Effects of Steroidal Chemosignals in Women and Men. Hormones and Behavior. 2000, 37: 57-78 [2011-05-19]. PMID 10712859. (原始內容存檔於2020-04-08). 
  6. ^ Hummer TA, McClintock MK. Putative human pheromone androstadienone attunes the mind specifically to emotional information. Horm Behav. April 2009, 55 (4): 548–59 [2011-05-18]. PMID 19470369. doi:10.1016/j.yhbeh.2009.01.002. (原始內容存檔於2018-02-11). 
  7. ^ Tamsin K. Saxton, Anna Lyndon, Anthony. Littlec and S. Craig Roberts. Evidence that androstadienone, a putative human chemosignal, modulates women’s attributions of men’s attractiveness. Hormones and Behavior. 2008, 54 (5): 597-601 [2022-02-13]. doi:10.1016/j.yhbeh.2008.06.001. (原始內容存檔於2011-02-23).