去甲漢黃芩素

化合物

去甲漢黃芩素(英語:Norwogonin,也稱為5,7,8-三羥基黃酮,5,7,8-trihydroxyflavone,縮寫5,7,8-THF)是一種天然黃酮類化合物,存在於黃芩(學名:Scutellaria baicalensis)等植物中[1]。其生物學活性接近7,8-二羥基黃酮(7,8-DHF)[2]

去甲漢黃芩素
臨床資料
其他名稱5,7,8-Trihydroxyflavone; 5,7,8-THF
識別資訊
  • 5,7,8-trihydroxy-2-phenylchromen-4-one
CAS號4443-09-8
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C15H10O5
摩爾質量270.24 g·mol−1
3D模型(JSmol英語JSmol
  • C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)O
  • InChI=1S/C15H10O5/c16-9-6-11(18)14(19)15-13(9)10(17)7-12(20-15)8-4-2-1-3-5-8/h1-7,16,18-19H
  • Key:ZFKKRRMUPBBYRS-UHFFFAOYSA-N

參考文獻

  1. ^ Miyasaki Y, Rabenstein JD, Rhea J, Crouch ML, Mocek UM, Kittell PE, et al. Khan AU , 編. Isolation and characterization of antimicrobial compounds in plant extracts against multidrug-resistant Acinetobacter baumannii. PLOS ONE. 2013, 8 (4): e61594. Bibcode:2013PLoSO...861594M. PMC 3632535 . PMID 23630600. doi:10.1371/journal.pone.0061594. 
  2. ^ Liu X, Chan CB, Jang SW, Pradoldej S, Huang J, He K, et al. A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect. Journal of Medicinal Chemistry. December 2010, 53 (23): 8274–86. PMC 3150605 . PMID 21073191. doi:10.1021/jm101206p.