SNAPC2

小核RNA激活蛋白复合体，多肽2，45千道尔顿
Small nuclear RNA activating complex, polypeptide 2, 45kDa
小核RNA激活蛋白复合体，多肽2，45千道尔顿; Small nuclear RNA activating complex, polypeptide 2, 45kDa
标识
代号	SNAPC2; PTFDELTA; SNAP45
扩展标识	遗传学：605076 鼠基因：1914861 同源基因：2318 GeneCards: SNAPC2 Gene
基因本体论描述
分子功能	· sequence-specific DNA binding transcription factor activity;
细胞成分	· nucleus; · nucleoplasm;
生物过程	· transcription from RNA polymerase II promoter; · transcription from RNA polymerase III promoter; · snRNA transcription; · gene expression;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体
物种	人类
Entrez	6618
Ensembl	ENSG00000104976
UniProt	Q13487
mRNA序列	NM_003083
蛋白序列	NP_003074
基因位置	Chr 19:; 7.99 – 7.99 Mb
PubMed查询	[1]
	查; 论; 编;

snRNA激活蛋白复合体第二亚基（英语：snRNA-activating protein complex subunit 2）是一个由人类基因SNAPC2编码的蛋白质^[1]^[2]。

相互作用

SNAPC2会与SNAPC4^[3]^[4]相互作用。

参考文献

^ Sadowski CL, Henry RW, Kobayashi R, Hernandez N. The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A. July 1996, 93 (9): 4289–93. PMC 39528  . PMID 8633057. doi:10.1073/pnas.93.9.4289.
^ Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa.
^ Wong, M W; Henry R W, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. (UNITED STATES). January 1998, 18 (1): 368–77. ISSN 0270-7306. PMC 121507  . PMID 9418884.
^ Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.

延伸阅读

Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995, 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0.
Maruyama K, Sugano S. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene. 1994, 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
Yoon JB, Roeder RG. Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol. Cell. Biol. Advances in Molecular and Cell Biology. 1996, 16 (1): 1–9. ISBN 978-0-7623-0143-0. PMC 230972  . PMID 8524284. doi:10.1016/S1569-2558(08)60061-2.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Gene. 1997, 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3.
Wong MW, Henry RW, Ma B; et al. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. 1998, 18 (1): 368–77. PMC 121507  . PMID 9418884.
Ma B, Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. 2001, 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200.
Acierno JS, Kennedy JC, Falardeau JL; et al. A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2. Genomics. 2001, 73 (2): 203–10. PMID 11318610. doi:10.1006/geno.2001.6526.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241  . PMID 12477932. doi:10.1073/pnas.242603899.
Hinkley CS, Hirsch HA, Gu L; et al. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J. Biol. Chem. 2003, 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200.
Gerhard DS, Wagner L, Feingold EA; et al. The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC). Genome Res. 2004, 14 (10B): 2121–7. PMC 528928  . PMID 15489334. doi:10.1101/gr.2596504.

[pmid8633057-1] Sadowski CL, Henry RW, Kobayashi R, Hernandez N. The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A. July 1996, 93 (9): 4289–93. PMC 39528  . PMID 8633057. doi:10.1073/pnas.93.9.4289.

[entrez-2] Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa.

[pmid9418884-3] Wong, M W; Henry R W, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. (UNITED STATES). January 1998, 18 (1): 368–77. ISSN 0270-7306. PMC 121507  . PMID 9418884.

[pmid11056176-4] Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.

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