5,7-二羟基色胺

化合物

5,7-二羟基色胺(英语:5,7-Dihydroxytryptamine,缩写5,7-DHT),分子式C10H12N2O2,是一种色胺衍生物[1],可作为神经毒素[2]

5,7-二羟基色胺
IUPAC名
3-(2-Aminoethyl)-1H-indole-5,7-diol
别名 5,7-Dihydroxytryptamine
识别
CAS号 31363-74-3  checkY
PubChem 35781
ChemSpider 32913
SMILES
 
  • Oc1cc2c(c(O)c1)[nH]cc2CCN
InChI
 
  • 1/C10H12N2O2/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14/h3-5,12-14H,1-2,11H2
InChIKey LXWHQTNFZDTKBH-UHFFFAOYAC
EINECS 250-591-6
性质
化学式 C10H12N2O2
摩尔质量 192.214 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Cairncross, KD; Cox, B; Forster, C; Wren, A. The ability of local injection of 6-OHDA, 5,6-DHT and 5,7-DHT into the olfactory bulbs to mimic the effects of bilateral bulbectomy in the rat proceedings. British Journal of Pharmacology. 1977, 61 (1): 145P–146P. PMC 1667625 . PMID 912193. doi:10.1111/j.1476-5381.1977.tb09748.x. 
  2. ^ Liu, J; Chu, YX; Zhang, QJ; Wang, S; Feng, J; Li, Q. 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus alters neuronal activity of the subthalamic nucleus in normal and 6-hydroxydopamine-lesioned rats. Brain Research. 2007, 1149: 216–22. PMID 17376410. S2CID 46596561. doi:10.1016/j.brainres.2007.02.052. 

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