阿魏酸

化合物

阿魏酸[1](英语:Ferulic acid4-羟-3-甲氧基肉桂酸3-(4-羟基-3-甲氧苯基)-2-丙烯酸)属于一种羟基苯丙烯酸,是存在于植物细胞壁中的一种丰富的酚类植物化学成分,例如它存在于阿拉伯木聚糖中共价连接的侧链中。

阿魏酸
IUPAC名
(E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid
别名 4-羟-3-甲氧基肉桂酸
3-(4-羟基-3-甲氧苯基)-2-丙烯酸
识别
CAS号 1135-24-6  checkY
PubChem 445858
ChemSpider 393368
SMILES
 
  • COc1cc(ccc1O)/C=C/C(=O)O
InChI
 
  • 1/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
InChIKey KSEBMYQBYZTDHS-HWKANZROBE
ChEBI 17620
DrugBank DB07767
性质
化学式 C10H10O4
摩尔质量 194.18 g·mol⁻¹
熔点 168-172 °C
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。
阿魏酸的紫外-可见光谱

参考文献

  1. ^ 全国科学技术名词审定委员会事务中心. 术语在线. [2019-03-12]. (原始内容存档于2019-07-13). 
  1. a Shahadi, Fereidoon; Naczk, Marian. Phenolics in food and nutraceuticals. Florida, USA: CRC Press LLC. 2004: 4. ISBN 1-58716-138-9. 
  2. a Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action. Breast Cancer Res. 2004; 6(2: R63-74. Epub 2003 Dec 15; PMID 14979919
  3. a b Role of NADPH oxidase-mediated generation of reactive oxygen species in the mechanism of apoptosis induced by phenolic acids in HepG2 human hepatoma cells. Arch Pharm Res. 2005 Oct; 28(10): 1183-9; PMID 16276977
  4. a Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. Carcinogenesis. 1983 Dec; 4(12): 1651-3; PMID 6317220
  5. a Chemopreventive effects of ferulic acid on oral and rice germ on large bowel carcinogenesis. Anticancer Res. 1999 Sep-Oct; 19(5A): 3775-8; PMID 10625957
  6. a Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J Invest Dermatol. 2005 Oct; 125(4): 826-32; PMID 16185284
  7. a Ferulic acid: an antioxidant found naturally in plant cell walls and feruloyl esterases involved in its release and their applications. Crit Rev Biotechnol. 2004; 24(2-3): 59-83; PMID 15493526
  8. a Biotechnological production of vanillin. Appl Microbiol Biotechnol. 2001 Aug; 56(3-4): 296-314; PMID 11548997
  9. a Beavis, R. C.; Chait, B. T., Cinnamic Acid Derivatives as Matrices for Ultraviolet Laser Desorption Mass Spectrometry of Proteins. Rapid Commun. Mass Spectrom. 1989, 3, 432-435; doi:10.1002/rcm.1290031207 PMID 2520223

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