茶碱乙酸

化合物

茶碱乙酸INN:Acefylline[1]),也称为醋茶碱,是黄嘌呤类的兴奋剂药物。它可作为腺苷受体拮抗剂。它与药物制剂乙苯海拉明中的苯海拉明结合,有助于抵消苯海拉明引起的睡意。[2]

茶碱乙酸
茶碱乙酸的骨架式
Ball-and-stick model of the acefylline molecule
临床资料
给药途径肌肉注射静脉注射
ATC码
识别信息
  • (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid
CAS号652-37-9  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.010.447 编辑维基数据链接
化学信息
化学式C9H10N4O4
摩尔质量238.20 g·mol−1
3D模型(JSmol英语JSmol
  • O=C2N(c1ncn(c1C(=O)N2C)CC(=O)O)C
  • InChI=1S/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15) checkY
  • Key:HCYFGRCYSCXKNQ-UHFFFAOYSA-N checkY

茶碱乙酸的硅烷醇甘露糖醛酸缀合物,乙酰茶碱甲基硅烷醇甘露糖醛酸酯(INCI;商品名Xantalgosil C),可作为脂解磷酸二酯酶抑制剂在市场上销售。它被用作药妆品的成分,用于治疗橘皮组织和用作皮肤调理剂。[3][4]

参见

参考资料

  1. ^ International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 21 (PDF). World Health Organization. [29 December 2016]. (原始内容存档 (PDF)于2022-01-19). 
  2. ^ Zuidema J. Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline. Thesis (doctoral)--Universiteit van Amsterdam. 1978 [2012-09-29]. (原始内容存档于2016-12-30). 
  3. ^ Biosil Technologies. Xantalgosil C® Datasheet (PDF). Exsymol S.A.M. 2005 [2022-01-20]. (原始内容存档于2023-12-04). 
  4. ^ Winter, Ruth. A Consumer's Dictionary of Cosmetic Ingredients 7th. Harmony/Rodale. 2009-10-20: 42 [2024-03-02]. ISBN 9780307459862. (原始内容存档于2024-03-07).