CD80
CD80(英語:Cluster of Differentiation 80,分化群80,也稱為B7-1)是一個位於3號染色體的人類基因,屬於免疫球蛋白超家族中的B7蛋白質家族[7],在樹突狀細胞、活化的B細胞、巨噬細胞以及T細胞上表達[8],與CD86(也稱為B7-2)形成共刺激信號[9]。
參考文獻
- ^ 與CD80相關的疾病;在維基數據上查看/編輯參考.
- ^ 對CD80起作用的藥物;在維基數據上查看/編輯參考.
- ^ 3.0 3.1 3.2 GRCh38: Ensembl release 89: ENSG00000121594 - Ensembl, May 2017
- ^ 4.0 4.1 4.2 GRCm38: Ensembl release 89: ENSMUSG00000075122 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mir MA. Introduction to Costimulation and Costimulatory Molecules. Developing Costimulatory Molecules for Immunotherapy of Diseases (Elsevier). 2015: 1–43. ISBN 978-0-12-802585-7. doi:10.1016/b978-0-12-802585-7.00001-7.
- ^ CD80 - T-lymphocyte activation antigen CD80 precursor - Homo sapiens (Human) - CD80 gene & protein. www.uniprot.org. [2021-06-09] (英語).
- ^ Peach RJ, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley PS. Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28. The Journal of Biological Chemistry. September 1995, 270 (36): 21181–7. PMID 7545666. doi:10.1074/jbc.270.36.21181 .
外部連結
- Human CD80 genome location and CD80 gene details page in the UCSC Genome Browser.