UR-144

UR-144
臨床資料
商品名（英語：Drug nomenclature）	different brandnames, typical example: "TMCP-018", "KM-X1", "UR-144", "MN-001", "YX-17"
法律規範狀態
法律規範	加：Schedule II; 德：Anlage II; 紐：Temporary Class; 英：Class B; 美：附表I;
識別資訊
	IUPAC命名法 (1-pentylindol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone; ;
CAS號	1199943-44-6
PubChem CID	44626619;
ChemSpider	24634882 ;
UNII	1TYA7HVP1B;
KEGG	C22781 ;
ChEMBL	ChEMBL571773 ;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID60152635 ;
化學資訊
化學式	C21H29NO
摩爾質量	311.47 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3C(C3(C)C)(C)C;
	InChI InChI=1S/C21H29NO/c1-6-7-10-13-22-14-16(15-11-8-9-12-17(15)22)18(23)19-20(2,3)21(19,4)5/h8-9,11-12,14,19H,6-7,10,13H2,1-5H3 ; Key:NBMMIBNZVQFQEO-UHFFFAOYSA-N ;

UR-144（也稱TMCP-018，KM-X1，MN-001，YX-17）是一種含氮有機化合物，分子式C₂₁H₂₉NO，由美國雅培公司開發^[2]，可作為大麻素受體2的完全激動劑。

參考文獻

Poso A, Huffman JW. Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands. British Journal of Pharmacology. January 2008, 153 (2): 335–346. PMC 2219524  . PMID 17982473. doi:10.1038/sj.bjp.0707567.
Chin CL, Tovcimak AE, Hradil VP, Seifert TR, Hollingsworth PR, Chandran P, et al. Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI. British Journal of Pharmacology. January 2008, 153 (2): 367–379. PMC 2219521  . PMID 17965748. doi:10.1038/sj.bjp.0707506.
Frost JM, Dart MJ, Tietje KR, Garrison TR, Grayson GK, Daza AV, et al. Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity. Journal of Medicinal Chemistry. March 2008, 51 (6): 1904–1912. PMID 18311894. doi:10.1021/jm7011613.