芫花素

化合物

芫花素(英語:Genkwanin)是一種芹菜素衍生的O-甲基化黃酮,為許多抗炎活性的草藥中主要活性成分[1]。提取自瑞香料植物芫花中,也存在於普通赤楊的種子等[2]

芫花素
Skeletal formula of genkwanin
Ball-and-stick model of genkwanin
IUPAC名
5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
別名 Gengkwanin
Apigenin 7-methyl ether
4',5-Dihydroxy-7-methoxyflavone
4',5-dihydroxy-7-methoxy flavone
5,4'-Dihydroxy-7-methoxyflavone
識別
CAS號 437-64-9  checkY=
PubChem 5281617
ChemSpider 4444936
SMILES
 
  • COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O
InChI
 
  • 1/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
InChIKey JPMYFOBNRRGFNO-UHFFFAOYAO
性質
化學式 C16H12O5
摩爾質量 284.27 g/mol g·mol⁻¹
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考資料

  1. ^ Gao Yuan; Fen Liu, Lei Fang, Runlan Cai, Chuanjie Zong, and Yun Qi. Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages. PloS one. 2014, 9 (5): e96741. 
  2. ^ O'Rourke, Ciara; Byres, Maureen; Delazar, Abbas; Kumarasamy, Yashodharan; Nahar, Lutfun; Stewart, Fiona; Sarker, Satyajit D. Hirsutanonol, oregonin and genkwanin from the seeds of Alnus glutinosa (Betulaceae). Biochemical Systematics and Ecology. 2005, 33 (7): 749–752 [2017-08-11]. doi:10.1016/j.bse.2004.10.005. (原始內容存檔於2012-08-23).