氰帕明

化合物

氰帕明INN:cianopramine,或稱為:3-氰基丙咪嗪,研發代號:Ro 11-2465)是一種含氮有機化合物,分子式C20H23N3,能作為三環類抗抑鬱藥(TCA)[1]5-羥色胺受體受體拮抗劑[2],從未上市銷售[3]

氰帕明
臨床資料
ATC碼
  • 未分配
識別資訊
  • 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine-3-carbonitrile
CAS號66834-24-0
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C20H23N3
摩爾質量305.43 g·mol−1
3D模型(JSmol英語JSmol
  • N#Cc1ccc3c(c1)N(c2ccccc2CC3)CCCN(C)C

參考文獻

  1. ^ Kenny M, Lenehan TJ, Lambe R, Darragh A, Brick I, Omer LM. Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers. Psychopharmacology. 1983, 79 (4): 304–7. PMID 6407042. S2CID 3112636. doi:10.1007/bf00433406. 
  2. ^ Pawłowski L, Kwiatek H, Górka Z. Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors?. Journal of Neural Transmission. 1981, 52 (1–2): 61–72. PMID 7288439. S2CID 41042435. doi:10.1007/BF01253098. 
  3. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 270–. ISBN 978-1-4757-2085-3. 

外部連結