1,8-萘啶

化合物

1,8-萘啶(英語:1,8-Naphthyridine,也稱為1,8-二氮雜萘)是萘啶(二氮雜萘,分子式C8H6N2)的同分異構體之一[2][3]。其衍生物有依諾沙星萘啶酸曲伐沙星等。1,8-萘啶在配位化學中是雙核配體英語binucleating ligand,即與兩個金屬原子配位的配體。[4][5]

1,8-萘啶
IUPAC名
1,8-Naphthyridine[1]
識別
CAS號 254-60-4
PubChem 136069
ChemSpider 119846
SMILES
 
  • C1=CC2=C(N=C1)N=CC=C2
Beilstein 109347
Gmelin 27124
EINECS 675-799-8
ChEBI 36628
性質
化學式 C8H6N2
摩爾質量 130.15 g·mol−1
外觀 黃色固體
密度 1.359 g/cm3
熔點 98-99 °C(272 K)
危險性
GHS危險性符號
《全球化學品統一分類和標籤制度》(簡稱「GHS」)中有害物質的標籤圖案
GHS提示詞 Warning
H-術語 H315, H319, H335
P-術語 P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ International Union of Pure and Applied Chemistry. Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013. The Royal Society of Chemistry. 2014: 212. ISBN 978-0-85404-182-4. doi:10.1039/9781849733069. 
  2. ^ Litvinov, Victor P.; Roman, Sergey V.; Dyachenko, Vladimir D. Naphthyridines. Structure, Physicochemical Properties and General Methods of Synthesis. Russian Chemical Reviews. 2000, 69 (3): 201–220. Bibcode:2000RuCRv..69..201L. S2CID 250827396. doi:10.1070/RC2000v069n03ABEH000553. 
  3. ^ Dapporto, P.; Ghilardi, C. A.; Mealli, C.; Orlandini, A.; Pacinotti, S. Low-Temperature (163 K) Structure of 1,8-Naphthyridine, C8H6N2. Acta Crystallographica Section C Crystal Structure Communications. 1984, 40 (5): 891–894. doi:10.1107/S0108270184006144. 
  4. ^ Hua, Shao-An; Liu, Isiah Po-Chun; Hasanov, Hasan; Huang, Gin-Chen; Ismayilov, Rayyat Huseyn; Chiu, Chien-Lan; Yeh, Chen-Yu; Lee, Gene-Hsiang; Peng, Shie-Ming. Probing the electronic communication of linear heptanickel and nonanickel string complexes by utilizing two redox-active [Ni2(napy)4]3+ moieties. Dalton Transactions. 2010, 39 (16): 3890–6. PMID 20372713. doi:10.1039/b923125k. 
  5. ^ Bera, Jitendra K.; Sadhukhan, Nabanita; Majumdar, Moumita. 1,8-Naphthyridine Revisited: Applications in Dimetal Chemistry. European Journal of Inorganic Chemistry. 2009, 2009 (27): 4023–4038. doi:10.1002/ejic.200900312.