1,4-二(2-氨乙基)哌嗪

化合物

1,4-二(2-氨乙基)哌嗪是一種有機化合物,化學式為C8H20N4。它可由哌嗪-1,4-二乙腈維基數據所列Q82031605氫化鋁鋰四氫呋喃中回流反應製得。[3]它和噻吩-2-甲醛英語Thiophene-2-carboxaldehyde在乙醇中反應,可以得到N,N'-二(2-噻吩亞甲基)-1,4-哌嗪二乙胺。[4]

1,4-二(2-氨乙基)哌嗪
識別
CAS號 6531-38-0  checkY
SMILES
 
  • NCCN1CCN(CCN)CC1
性質
化學式 C8H20N4
摩爾質量 172.27 g·mol−1
外觀 無色固體[1]
熔點 34-36 °C[1]
40 °C[2]
沸點 100 °C(0.3 mmHg)[1]
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ 1.0 1.1 1.2 Purchase, Rupert (2005). The purification of triethylenetetramine and its dihydrochloride for the treatment of Wilson's disease. Journal of Chemical Research, 2005 (4), 233–235. doi:10.3184/0308234054213375
  2. ^ von Braun, Julius; Goll, Otto; Metz, Ernst. Pharmacological behavior of the allphatic diamines. Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen, 1926. 59B: 2416-2425. ISSN 0365-9488.
  3. ^ Rosanna Filosa; et al. Bioorganic & Medicinal Chemistry, 2009. 17 (1): 13-24. doi:10.1016/j.bmc.2008.11.024.
  4. ^ Hassan Keypour, Majid Rezaeivala, and Ahmad Ali Dehghani-Firouzabadi. Synthesis and Characterisation of Some Hexadentate Schiff-base Ligands Containing the Piperazine Moiety. Journal of Chemical Research, 2009. 2. 126-128. doi:10.3184/030823409X402528.