昂特納貝

昂特納貝INNonternabez,開發代號:HU-308PPP-003ARDS-003),分子式C27H42O3,是一種人工合成的HU系列大麻素,由耶路撒冷希伯來大學拉斐爾·梅舒朗團隊在1990年代晚期開發[1][2][3]

昂特納貝
法律規範狀態
法律規範
藥物動力學數據
藥物代謝
排泄途徑
識別資訊
  • [(1S,2S,5S)-2-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol
CAS號256934-39-1  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C27H42O3
摩爾質量414.63 g·mol−1
3D模型(JSmol英語JSmol
  • CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC)[C@H]2C=C([C@@H]3C[C@H]2C3(C)C)CO)OC
  • InChI=1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21-,22+/m0/s1
  • Key:CFMRIVODIXTERW-FDFHNCONSA-N

參考文獻

  1. ^ Mechoulam R, Lander N, Breuer A, Zahalka J. Synthesis of the individual, pharmacologically distinct enantiomers of a tetrahydrocannabinol derivative. Tetrahedron Asymmetry. 1990-04-11, 1 (5): 315–318. doi:10.1016/S0957-4166(00)86322-3  (英語). 
  2. ^ Hanus L, Breuer A, Tchilibon S, Shiloah S, Goldenberg D, Horowitz M, et al. HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor. Proceedings of the National Academy of Sciences of the United States of America. December 1999, 96 (25): 14228–14233. Bibcode:1999PNAS...9614228H. PMC 24419 . PMID 10588688. doi:10.1073/pnas.96.25.14228 . 
  3. ^ Properties of HU-308 ~ Formula C27H42O3. Pitt Quantum Repository. University of Pittsburgh Department of Chemistry. [2024-06-10]. (原始內容存檔於2022-08-17). 

外部連結