心律失常性猝死綜合徵

心律失常性猝死綜合徵[1](sudden arrhythmic death syndrome,SADS)舊名突發性猝死綜合徵(sudden unexpected death syndrome,SUDS)、突發性夜間猝死綜合徵(sudden unexpected nocturnal death syndrome),是一種突發而不能預測的心源性死亡,經屍檢、組織學、毒理學研究均不能解釋的綜合徵,多數患者有遺傳性心臟病;患此病的青少年或成人在睡眠時會突然死亡[2]布魯格達氏綜合徵是其中一種相對常見的類型[3]

此綜合徵於1977年在美國的苗族難民中首次發現[4][5]。此後新加坡的一項回顧性調查又發現,1982年至1990年間有230名健康的泰國人因不明原因突然死亡[6]。在菲律賓本土方言中該病被稱為「bangungot」(意為睡眠中呻吟),每年平均10萬人中有43人因此喪命,病人多為年輕男性[7]

研究發現bangungot患者並無器質性的心臟病變,但發病時有心律不齊、心室顫動的症狀。現在仍無法預防此病的發生,發病後則可以通過除顫器進行治療。菲律賓傳統上會使用扭動患者拇趾的方法使其心律恢復正常[8]

菲律賓的大多bangungot病例與急性出血性胰腺炎(acute hemorrhagic pancreatitis)有關[9]泰國老撾的bangungot則由布魯格達氏症候群導致[10]

參見

參考文獻

  1. ^ 帥維,洪葵. 心律失常性猝死成人和兒童家族成員的臨床管理[J]. 臨床心血管病雜誌,2015,31(12):1259-1261. DOI:10.13201/j.issn.1001-1439.2015.12.003.
  2. ^ Also known as SUDS. See: Reddy PR, Reinier K, Singh T, Mariani R, Gunson K, Jui J, Chugh SS. Physical activity as a trigger of sudden cardiac arrest: The Oregon Sudden Unexpected Death Study. Int J Cardiol. 2008
  3. ^ Brugada Syndrome. NORD (National Organization for Rare Disorders). 2016 [28 October 2017]. (原始內容存檔於2017-02-11). 
  4. ^ Centers for Disease Control (CDC). Sudden, unexpected, nocturnal deaths among Southeast Asian refugees. MMWR. Morbidity and mortality weekly report. 1981, 30 (47): 581–4,589. PMID 6796814. 
  5. ^ Parrish RG, Tucker M, Ing R, Encarnacion C, Eberhardt M. Sudden unexplained death syndrome in Southeast Asian refugees: a review of CDC surveillance. MMWR CDC Surveil Summ. 1987, 36 (1): 43SS–53SS. PMID 3110586. 
  6. ^ Goh KT, Chao TC, Chew CH. Sudden nocturnal deaths among Thai construction workers in Singapore. Lancet. 1990, 335 (8698): 1154. PMID 1971883. doi:10.1016/0140-6736(90)91153-2. 
  7. ^ Gervacio-Domingo, G.; F . Punzalan , M . Amarillo , A . Dans. Sudden unexplained death during sleep occurred commonly in the general population in the Philippines: a sub study of the National Nutrition and Health Survey .. Journal of Clinical Epidemiology: 561–571. [2008-12-09]. (原始內容存檔於2018-07-01). 
  8. ^ Ramos, Maximo D. Creatures of Philippine Lower Mythology. Philippines: University of the Philippines Press. 1971. 
  9. ^ Munger, Ronald G.; Elizabeth A. Booton. Bangungut in Manila: sudden and unexplained death in sleep of adult Filipinos (PDF). International Journal of Epidemiology. 1998, 27 (4): 677–684 [2011-07-29]. PMID 9758125. doi:10.1093/ije/27.4.677. (原始內容 (PDF)存檔於2015-09-30). 
  10. ^ http://www.inq7.net/lif/2004/jun/19/lif_7-1.htm (link broken as of 3 October 2007).. [2012-04-27]. (原始內容存檔於2004-06-30).  外部連結存在於|title= (幫助)