细胞黏附
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细胞黏附是指细胞透过表面的特殊分子，和邻近细胞或细胞外基质相互作用并且结合的过程。此过程可以透过两个细胞的直接接触（例如细胞连接），也可以间接地由细胞附著在细胞外基质上来达成。细胞外基质是细胞所释出的物质，可以填满细胞周围的空间[1]。细胞黏附主要是由细胞表面细胞黏附分子（CAM，一种跨膜蛋白）所介导[2]。细胞黏附会连接各细胞，且参与细胞的信号传导，使细胞能够感知并回应周围环境的变化[1][3]。细胞黏附在多细胞生物的组织形成、细胞迁移等过程中扮演重要角色[4]。细胞黏附的异常与多种疾病（如癌症[5][6]及关节炎[7]）密切相关，同时也影响感染原（细菌或病毒）的疾病传播[8][9]。
相关条目
参考资料
- ^ 1.0 1.1 Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Molecular Biology of the Cell. 6th. Garland Science. 2014. ISBN 9780815344322.
- ^ Lodish, Harvey; Berk, Arnold; Matsudaira, Paul; Kaiser, Chris A.; Krieger, Monty; Scott, Matthew P.; Zipursky, Lawrence; Darnell, James. Molecular Cell Biology 5th. W.H. Freeman. 2003. ISBN 978-0716743668.
- ^ Gumbiner, Barry M. Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis. Cell. 1996, 84 (3): 345–357. PMID 8608588. S2CID 13443584. doi:10.1016/S0092-8674(00)81279-9
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- ^ Sumigray, Kaelyn D.; Lechler, Terry. Cell Adhesion in Epidermal Development and Barrier Formation 112. 2015: 383–414. ISBN 9780124077584. PMC 4737682 . PMID 25733147. doi:10.1016/bs.ctdb.2014.11.027.
|journal=被忽略 (帮助) - ^ Okegawa, T; Pong, RC; Li, Y; Hsieh, JT. The role of cell adhesion molecule in cancer progression and its application in cancer therapy.. Acta Biochimica Polonica. 2004, 51 (2): 445–57. PMID 15218541. doi:10.18388/abp.2004_3583 .
- ^ Hirohashi, Setsuo; Kanai, Yae. Cell adhesion system and human cancer morphogenesis. Cancer Science. 2003, 94 (7): 575–581. PMC 11160151 . PMID 12841864. S2CID 22154824. doi:10.1111/j.1349-7006.2003.tb01485.x .
- ^ Szekanecz, Zoltan; Koch, Alisa E. Cell–cell interactions in synovitis: Endothelial cells and immune cell migration. Arthritis Research. 2000, 2 (5): 368–373. PMC 130138 . PMID 11094450. doi:10.1186/ar114 .
- ^ Pizarro-Cerdá, Javier; Cossart, Pascale. Bacterial Adhesion and Entry into Host Cells. Cell. 2006, 124 (4): 715–727. PMID 16497583. S2CID 5769387. doi:10.1016/j.cell.2006.02.012 .
- ^ Mateo, M.; Generous, A.; Sinn, P. L.; Cattaneo, R. Connections matter - how viruses use cellcell adhesion components. Journal of Cell Science. 2015, 128 (3): 431–439. PMC 4311127 . PMID 26046138. doi:10.1242/jcs.159400.
外部链接
- The Cell （页面存档备份，存于互联网档案馆） by G. Cooper (online textbook)
- Molecular Cell Biology （页面存档备份，存于互联网档案馆） by Lodish et al. (online textbook)
- Molecular Biology of the Cell （页面存档备份，存于互联网档案馆） by Alberts et al. (online textbook)
- Cell Adhesion and Extracellular Matrix - The Virtual Library of Biochemistry, Molecular Biology and Cell Biology （页面存档备份，存于互联网档案馆）