帕曲妥单抗
化合物
帕曲妥单抗（INN：Patritumab）是一种人单克隆抗体，设计用于治疗非小细胞肺癌。它充当免疫调节剂。[1][2]
| 单克隆抗体 | |
|---|---|
| 种类 | 完整抗体 |
| 目标 | HER3 |
| 临床资料 | |
| ATC码 |
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| 识别信息 | |
| CAS号 | 1262787-83-6 |
| ChemSpider |
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| UNII | |
| KEGG | |
临床试验
它正在进行针对头颈部鳞状细胞癌的二期临床试验。[3]
参考资料
- ^ World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 106 (PDF). WHO Drug Information. 2011, 25 (4) [2024-01-24]. （原始内容存档 (PDF)于2016-03-04）.
- ^ Horinouchi H. The prospect of patritumab for treating non-small cell lung cancer. Expert Opinion on Biological Therapy. December 2016, 16 (12): 1549–1555. PMID 27744717. S2CID 4035336. doi:10.1080/14712598.2016.1249846.
- ^ Clinical trial number NCT02633800 for "A Clinical Trial Using Patritumab or Placebo in Combination With Cetuximab and a Platinum Agent for Patients With Squamous Cell Cancer of the Head and Neck" at ClinicalTrials.gov
- ^ Anti-HER3 Monoclonal Antibody Patritumab Selected for I-SPY 2 TRIAL in Breast Cancer. October 2016 [2024-01-24]. （原始内容存档于2024-01-24）.