对苯二乙酸
化合物
| 对苯二乙酸 | |
|---|---|
| |
| 别名 | 1,4-苯二乙酸 苯-1,4-二乙酸 |
| 缩写 | H2PDA H2phda |
| 识别 | |
| CAS号 | 7325-46-4 
|
| 性质 | |
| 化学式 | C10H10O4 |
| 摩尔质量 | 194.18 g·mol⁻¹ |
| 外观 | 固体 |
| 密度 | 1.345±0.06 g·cm−3[1] |
| 熔点 | 253—254 °C（526—527 K）[2] |
| 溶解性（水） | 微溶于水[3] |
| 相关物质 | |
| 相关化学品 | 对苯二甲酸 苯乙酸 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
制备
对苯二乙酸可由对苯二乙腈在盐酸溶液中于100°C水解反应制得。[4]
- NCCH2C6H4CH2CN + H2O → HOOCCH2C6H4CH2COOH
化学性质
对苯二乙酸可以和一些过渡金属盐反应，如混合配体的镉配合物的制备[7]；和镧系金属的盐类的反应也有报道，如在溶剂热（水：乙醇＝10：1）的条件下和硝酸钕反应，生成[Nd2(PDA)3(H2O)]·2H2O。[8]
参考文献
- ^ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2018 ACD/Labs). Retrieved from SciFinder. [2018-11-30]
- ^ Schwenk, Erwin; Journal of Organic Chemistry 1946, V11, P798-802 CAPLUS
- ^ 1,4-苯二乙酸. Chemical Book. [2018-11-30]
- ^ Matthew Badland, Michael P. Burns, Robert J. Carroll, Roger M. Howard, Daniel Laity, Nathan J. Wymer. Application of biocatalysis towards asymmetric reduction and hydrolytic desymmetrisation in the synthesis of a β-3 receptor agonist. Green Chemistry. 2011, 13 (10): 2888 [2018-11-30]. ISSN 1463-9262. doi:10.1039/c1gc15694b. （原始内容存档于2018-06-03） （英语）.
- ^ Meng-yao She, Da-wei Xiao, Bing Yin, Zheng Yang, Ping Liu, Jian-li Li, Zhen Shi. An efficiently cobalt-catalyzed carbonylative approach to phenylacetic acid derivatives. Tetrahedron. 2013-09, 69 (35): 7264–7268 [2018-11-30]. ISSN 0040-4020. doi:10.1016/j.tet.2013.06.083. （原始内容存档于2020-02-10）.
- ^ Li, Jianli; Pang, Peng; Xiao, Dawei. 2-(2-Carboxylphenyl)benzimidazole cobalt complex and application in synthesis of phenylacetic acid or its derivatives. Faming Zhuanli Shenqing, 2013. 7. 10, CN 103193829 A
- ^ Chunying Xu, Linke Li, Yinping Wang, Qianqian Guo, Xianjuan Wang, Hongwei Hou, Yaoting Fan. Three-Dimensional Cd(II) Coordination Polymers Based on Semirigid Bis(Methylbenzimidazole) and Aromatic Polycarboxylates: Syntheses, Topological Structures and Photoluminescent Properties. Crystal Growth & Design. 2011-10-05, 11 (10): 4667–4675 [2018-11-30]. ISSN 1528-7483. doi:10.1021/cg200961a （英语）.
- ^ Zilu Chen, Wei Xiong, Zhong Zhang, Fupei Liang. Structure and Magnetic Properties of Two Lanthanide 1,4-Phenylenediacetate Compounds. Zeitschrift für anorganische und allgemeine Chemie. 2009-11-27, 636 (7): 1392–1396 [2018-11-30]. ISSN 0044-2313. doi:10.1002/zaac.200900452 （英语）.