人参炔三醇

人参炔三醇(英语:Panaxytriol)是一种在人参根部提取物中发现的脂肪醇,分子式C
17
H
26
O
3
[1]。该分子可能具有抗肿瘤活性[2]。该分子已被全合成,反应涉及细菌环氧化酶的应用,因而避免了立体异构体的问题[3]

人参炔三醇
IUPAC名
(3R,9S,10S)-Heptadec-1-en-4,6-diyne-3,9,10-triol
识别
CAS号 87005-03-6  checkY
PubChem 11108666
ChemSpider 9283802
SMILES
 
  • CCCCCCC[C@@H]([C@H](CC#CC#C[C@@H](C=C)O)O)O
性质
化学式 C17H26O3
摩尔质量 278.39 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考资料

  1. ^ Shim, Sang Chul; Koh, Hun Yeoung; Han, Byung Hoon. Polyacetylenes from Panax ginseng roots. Phytochemistry. 1983, 22 (8): 1817–18. doi:10.1016/S0031-9422(00)80278-2. 
  2. ^ MATSUNAGA, Hisashi; et al. Studies on the panaxytriol of Panax ginseng CA Meyer. Isolation, determination and antitumor activity. Chemical and pharmaceutical bulletin. 1989, 37 (5): 1279-1281. 
  3. ^ Mayer, Sandra F. Chemoenzymatic Asymmetric Total Syntheses of Antitumor Agents (3 R, 9 R, 10 R)-and (3 S, 9 R, 10 R)-Panaxytriol and (R)-and (S)-Falcarinol from Panax g inseng Using an Enantioconvergent Enzyme-Triggered Cascade Reaction. The Journal of organic chemistry. 2002, 67 (26): 9115-9121.