胞移作用
胞移作用（英語：Transcytosis）是指大分子通過細胞的內部，大分子是在細胞的某一側以囊泡進入細胞，穿越整個細胞，再從另一側出去。這些大分子包含抗體中的IgA[1]、運鐵蛋白[2]以及胰島素[3]。最常發生胞移作用的細胞是上皮細胞，但其他組織的細胞諸如血管中的微血管[4]就經常被提及；其他可以看到此一現象的組織有神經細胞[5]、蝕骨細胞[6]、小腸中的微皺細胞[7]
調控
胞移作用在不同的組織中變化甚大，許多組織的胞移作用的特殊點被標示出來。布雷非德菌素A通常被用來當作內質網到高爾基體之囊狀小泡的阻斷劑，最先在狗的腎臟細胞中在發現自然界中的胞移作用[8]。另外在表層細胞膜上可以發現RAB17[9]、RAB11A'[10]
參考文獻
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- ^ S. K. Williams, D. A. Greener, N. J. Solenski. Endocytosis and exocytosis of protein in capillary endothelium. Journal of Cellular Physiology. 1984-08, 120 (2): 157–162 [2019-07-11]. ISSN 0021-9541. PMID 6430919. doi:10.1002/jcp.1041200208. （原始内容存档于2019-08-19）.
- ^ R. H. Fabian. Retrograde axonal transport and transcytosis of immunoglobulins: implications for the pathogenesis of autoimmune motor neuron disease. Advances in Neurology. 1991, 56: 433–444 [2019-07-11]. ISSN 0091-3952. PMID 1853776. （原始内容存档于2019-08-24）.
- ^ J. Salo, P. Lehenkari, M. Mulari, K. Metsikkö, H. K. Väänänen. Removal of osteoclast bone resorption products by transcytosis. Science (New York, N.Y.). 1997-04-11, 276 (5310): 270–273 [2019-07-11]. ISSN 0036-8075. PMID 9092479. doi:10.1126/science.276.5310.270. （原始内容存档于2019-08-20）.
- ^ T. Landsverk. The follicle-associated epithelium of the ileal Peyer's patch in ruminants is distinguished by its shedding of 50 nm particles. Immunology and Cell Biology. 1987-06,. 65 ( Pt 3): 251–261 [2019-07-11]. ISSN 0818-9641. PMID 3623609. doi:10.1038/icb.1987.28. （原始内容存档于2019-08-14）.
- ^ M. E. Taub, W. C. Shen. Regulation of pathways within cultured epithelial cells for the transcytosis of a basal membrane-bound peroxidase-polylysine conjugate. Journal of Cell Science. 1993-12,. 106 ( Pt 4): 1313–1321 [2019-07-11]. ISSN 0021-9533. PMID 8126110. （原始内容存档于2019-08-24）.
- ^ W. Hunziker, P. J. Peters. Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. The Journal of Biological Chemistry. 1998-06-19, 273 (25): 15734–15741 [2019-07-11]. ISSN 0021-9258. PMID 9624171. doi:10.1074/jbc.273.25.15734. （原始内容存档于2019-08-19）.
- ^ J. E. Casanova, X. Wang, R. Kumar, S. G. Bhartur, J. Navarre, J. E. Woodrum, Y. Altschuler, G. S. Ray, J. R. Goldenring. Association of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby canine kidney cells. Molecular Biology of the Cell. 1999-01, 10 (1): 47–61 [2019-07-11]. ISSN 1059-1524. PMC 25153 . PMID 9880326. doi:10.1091/mbc.10.1.47. （原始内容存档于2019-08-27）.
