CYP1A2

细胞色素P450 1A2（英语：Cytochrome P450 1A2） （缩写为CYP1A2），是细胞色素P450混合功能氧化酶家族的一员，参与体内异生物质的代谢。CYP1A2酶由人类CYP1A2基因编码。

Cytochrome P450, family 1, subfamily A, polypeptide 2
PDB根据2hi4所绘制的渲染图
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 2HI4
标识
代号	CYP1A2; CP12; P3-450; P450(PA)
扩展标识	遗传学：124060 鼠基因：88589 同源基因：68082 ChEMBL: 3356 GeneCards: CYP1A2 Gene
EC编号	1.14.14.1
基因本体论描述 分子功能 · monooxygenase activity · iron ion binding · electron carrier activity · oxidoreductase activity · oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen · enzyme binding · heme binding · demethylase activity · caffeine oxidase activity · aromatase activity 细胞成分 · endoplasmic reticulum membrane · intracellular membrane-bounded organelle 生物过程 · steroid catabolic process · porphyrin-containing compound metabolic process · xenobiotic metabolic process · toxin biosynthetic process · post-embryonic development · alkaloid metabolic process · regulation of gene expression · monoterpenoid metabolic process · drug metabolic process · dibenzo-p-dioxin metabolic process · arachidonic acid metabolic process · epoxygenase P450 pathway · lung development · methylation · response to estradiol · response to lipopolysaccharide · monocarboxylic acid metabolic process · response to immobilization stress · drug catabolic process · exogenous drug catabolic process · small molecule metabolic process · cellular respiration · heterocycle metabolic process · hydrogen peroxide biosynthetic process · oxidation-reduction process · oxidative demethylation · cellular response to cadmium ion · oxidative deethylation · omega-hydroxylase P450 pathway Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	1544	13077
Ensembl	ENSG00000140505	ENSMUSG00000032310
UniProt	P05177	P00186
mRNA序列	NM_000761	NM_009993
蛋白序列	NP_000752	NP_034123
基因位置	Chr 15: 74.75 – 74.76 Mb	Chr 9: 57.68 – 57.68 Mb
PubMed查询	[1]	[2]

延伸阅读

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