1-異硫氰基-6-甲亞磺酰基己烷
化合物
1-異硫氰基-6-甲亞磺酰基己烷或異硫氰酸-6-甲亞磺酰基己酯是一種有機化合物，化學式為C8H15NOS2。它可由6-溴己腈、甲硫醇鈉、二硫化碳和間氯過氧苯甲酸為原料反應得到。[1]它存在於山葵中，是一種糖原合酶激酶3β抑制劑。[2]有文獻對其抗癌作用做了小鼠實驗。[3]
| 1-異硫氰基-6-甲亞磺酰基己烷 | |
|---|---|
hexyl_isothiocyanate.svg)
| |
| IUPAC名 1-Isothiocyanato-6-(methanesulfinyl)hexane | |
| 別名 | 6-MITC; 6-MSITC 異硫氰酸(6-甲亞磺酰基)己酯 (6-甲基亞磺酰基)己基硫氰酸酯 |
| 識別 | |
| CAS號 | 4430-35-7 
|
| PubChem | 9815648 |
| ChemSpider | 7991398 |
| SMILES |
|
| ChEBI | 138799 |
| 性質 | |
| 化學式 | C8H15NOS2 |
| 摩爾質量 | 205.34 g·mol−1 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
參考文獻
- ^ Ashida, Hitoshi; Hashimoto, Takashi. Cell cycle inhibitors containing Brassicaceae isothiocyanates, and topical preparations, cosmetics, and health foods containing them. 2006 JP 2006089394 A.
- ^ Jun Yoshida, Satomi Nomura, Naoyuki Nishizawa, Yoshiaki Ito, Ken-ichi Kimura. Glycogen Synthase Kinase-3β Inhibition of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi ( Wasabia japonica Matsum). Bioscience, Biotechnology, and Biochemistry. 2011-01-23, 75 (1): 136–139 [2022-02-26]. ISSN 0916-8451. doi:10.1271/bbb.100507 （英語）.
- ^ Yoko Fuke, Yoshiko Haga, Haruhiro Ono, Takahiro Nomura, Kazuo Ryoyama. Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.). Cytotechnology. 1997-11-01, 25 (1): 197 [2022-02-26]. ISSN 1573-0778. PMC 3466737
. PMID 22358892. doi:10.1023/A:1007918508115 （英語）.
