靶点 (生物学)
生物学靶点（英语：Biological target）是指位于生物体内，能够被其他物质（配体、药物等）识别或结合的结构。比如，一些微生物的趋化性（chemotaxis）系统中的甲基趋化受体蛋白（methyl-accepting chemotaxis protein）能够被其生存环境中的一些分子（葡萄糖等）结合，进而调节微生物的鞭毛运动。常见的药物靶点包括蛋白质、核酸和离子通道等。
药物靶点
参考文献
- ^ Trends in the exploitation of novel drug targets. Nature Reviews Drug Discovery: 579-590. doi:10.1038/nrd3478.
- ^ 作为2型糖尿病治疗药物的G蛋白偶联受体40激动剂研究进展.
- ^ Drug Design Strategies for Targeting G‐Protein‐Coupled Receptors.
- ^ PTP1B as a drug target: recent developments in PTP1B inhibitor discovery. [2019-01-02]. （原始内容存档于2013-03-11）.
- ^ Ion Channels as Drug Targets in Central Nervous System Disorders.
- ^ Ion Channels as Drug Targets: The Next GPCRs.
- ^ Recent Advances in Developing Small Molecules Targeting Nucleic Acid.