鳞状细胞癌抗原-2

位於18號人類染色體的基因

鳞状细胞癌抗原-2(英語:Squamous cell carcinoma antigen-2,缩写SCCA-2SCCA2,也称为丝氨酸蛋白酶抑制剂家族B亚家族成员4serpin family B member 4,缩写SERPINB4)是一个人类18号染色体上的基因,编码一种丝氨酸蛋白酶抑制剂蛋白,是鳞状细胞癌肿瘤标志物[5][6][7]

鳞状细胞癌抗原-2
識別號
别名SERPINB4;, LEUPIN, PI11, SCCA-2, SCCA1, SCCA2, serpin family B member 4
外部IDOMIM600518 MGI2683293 HomoloGene76659 GeneCardsSERPINB4
基因位置(人类
18號染色體
染色体18號染色體[1]
18號染色體
鳞状细胞癌抗原-2的基因位置
鳞状细胞癌抗原-2的基因位置
基因座18q21.33起始63,637,259 bp[1]
终止63,644,256 bp[1]
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

​NM_002974
​NM_175041

NM_198680

蛋白序列

NP_002965
​NP_778206

NP_941373

基因位置​(UCSC)Chr 18: 63.64 – 63.64 MbChr 1: 107.08 – 107.21 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000206073 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000073602 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A. May 1995, 92 (8): 3147–51. Bibcode:1995PNAS...92.3147S. PMC 42122 . PMID 7724531. doi:10.1073/pnas.92.8.3147 . 
  6. ^ Sakata Y, Arima K, Takai T, Sakurai W, Masumoto K, Yuyama N, Suminami Y, Kishi F, Yamashita T, Kato T, Ogawa H, Fujimoto K, Matsuo Y, Sugita Y, Izuhara K. The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1. J Biol Chem. Feb 2004, 279 (7): 5081–7. PMID 14630915. doi:10.1074/jbc.M311585200 . 
  7. ^ Entrez Gene: SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4. [2023-04-10]. (原始内容存档于2010-12-05). 

外部链接