间苯胺黄

间苯胺黄酸性黄36)是一种偶氮染料。在分析化学中,间苯胺黄可用作酸碱指示剂,它的变色范围是pH值1.2 - 3.2,从红色变为黄色。[1]

间苯胺黄
IUPAC名
Sodium 3-[(4-anilinophenyl)diazenyl]benzenesulfonate
别名 C.I.酸性黄36; Acid Metanil Yellow; Monoazo; 4-[(3-苯氨基苯基)偶氮基]苯磺酸钠
识别
CAS号 587-98-4  checkY
PubChem 3935589
SMILES
 
  • C1=CC=C(C=C1)NC2=CC=C(C=C2)N=NC3=CC(=CC=C3)S(=O)(=O)[O-].[Na+]
InChI
 
  • 1S/C18H15N3O3S.Na/c22-25(23,24)18-8-4-7-17(13-18)21-20-16-11-9-15(10-12-16)19-14-5-2-1-3-6-14;/h1-13,19H,(H,22,23,24);/q;+1/p-1
InChIKey NYGZLYXAPMMJTE-UHFFFAOYSA-M
性质
化学式 C18H15N3NaO3S
摩尔质量 376.38 g·mol−1
熔点 > 250 °C
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

虽然间苯胺黄没有被批准作为食物染色剂,但在印度,间苯胺黄有被部分商家充当姜黄粉和木豆混淆品[2][3][4][5]

相关的动物研究表明,间苯胺黄具有神经毒性[3]肝毒性英语hepatotoxic[6]

参考资料

  1. ^ R. W. Sabnis. Handbook of Acid-Base Indicators. Boca Raton: CRC Press英语CRC Press. 2007: 219. ISBN 978-0-8493-8219-2. 
  2. ^ Dhakal, S; Chao, K; Schmidt, W; Qin, J; Kim, M; Chan, D. Evaluation of Turmeric Powder Adulterated with Metanil Yellow Using FT-Raman and FT-IR Spectroscopy. Foods. 2016, 5 (2): 36. PMC 5302347 . PMID 28231130. doi:10.3390/foods5020036. 
  3. ^ 3.0 3.1 Nagaraja, T. N; Desiraju, T. Effects of chronic consumption of metanil yellow by developing and adult rats on brain regional levels of noradrenaline, dopamine and serotonin, on acetylcholine esterase activity and on operant conditioning. Food and Chemical Toxicology. 1993, 31 (1): 41–4. PMID 8095244. doi:10.1016/0278-6915(93)90177-z. 
  4. ^ Nath, P. P., Sarkar, K., Tarafder, P., Mondal, M., Das, K. and Paul, G. Practice of using metanil yellow as food colour to process food in unorganized sector of West Bengal (PDF). International Food Research Journal. 2015, 22 (4): 1424–1428 [2021-04-23]. (原始内容存档 (PDF)于2020-07-13). 
  5. ^ "Common food adulterants in India", [[今日印度|India Today]], New Delhi, October 19, 2018. [2021-04-23]. (原始内容存档于2021-04-23). 
  6. ^ Saxena, B; Sharma, S. Food Color Induced Hepatotoxicity in Swiss Albino Rats, Rattus norvegicus. Toxicology International. 2015, 22 (1): 152–157. PMC 4721164 . PMID 26862277. doi:10.4103/0971-6580.172286.