羊茅麦角碱

化合物

羊茅麦角碱((8β,10β)-6,8-二甲基麦角灵)是一种有机化合物,化学式为C16H20N2,它是一种麥角靈真菌分离物。[2]它可以2-溴-3-硝基苄溴为原料经多步反应、柱分离制得。[1]

羊茅麦角碱
IUPAC名
6,8β-Dimethylergoline
系统名
(6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
别名 狐茅麦角碱
识别
CAS号 569-26-6  checkY
PubChem 332915
ChemSpider 294963
SMILES
 
  • C[C@@H]1C[C@@H]2c3cccc4c3c(c[nH]4)C[C@H]2N(C1)C
性质
化学式 C16H20N2
摩尔质量 240.34 g·mol−1
外观 白色固体[1]
熔点 236—240 °C(509—513 K)[1]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ 1.0 1.1 1.2 Liu, Haichao; Zhang, Xiwu; Shan, Dong; Pitchakuntla, Mallesham; Ma, Yongfan; Jia, Yanxing. Total Syntheses of Festuclavine, Pyroclavine, Costaclavine, epi-Costaclavine, Pibocin A, 9-Deacetoxyfumigaclavine C, Fumigaclavine G, and Dihydrosetoclavine. Organic Letters (American Chemical Society (ACS)). 2017-06-08, 19 (12): 3323–3326. ISSN 1523-7060. doi:10.1021/acs.orglett.7b01504. 
  2. ^ Wallwey, C; Matuschek, M; Xie, XL; Li, SM. Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3. Organic & Biomolecular Chemistry. 2010, 8 (15): 3500–8. PMID 20526482. doi:10.1039/c003823g.