川陈皮素

化合物

川陈皮素(英語:Nobiletin,也称为蜜橘黄素川皮亭5,6,7,8,3',4'-六甲氧基黄酮,3′,4′,5,6,7,8-Hexamethoxyflavone)是一种O-甲基化黄酮,分子式C21H22O8,存在于许多柑橘果皮[1]

Nobiletin
Skeletal formula of nobiletin
Ball-and-stick model of nobiletin
IUPAC名
3′,4′,5,6,7,8-Hexamethoxyflavone
别名 Hexamethoxyflavone
识别
CAS号 478-01-3  checkY
PubChem 72344
ChemSpider 65283
SMILES
 
  • c1c(OC)c(OC)ccc1C2=CC(=O)c3c(OC)c(OC)c(OC)c(OC)c3O2
InChI
 
  • 1/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
InChIKey MRIAQLRQZPPODS-UHFFFAOYAI
ChEBI 7602
KEGG C10112
性质
化学式 C21H22O8
摩尔质量 402.39 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Nagase H, Yamakuni T, Matsuzaki K, Maruyama Y, Kasahara J, Hinohara Y, Kondo S, Mimaki Y, Sashida Y, Tank AW, Fukunaga K, Ohizumi Y. Mechanism of Neurotrophic Action of Nobiletin in PC12D Cells. Biochemistry. 2005, 44 (42): 13683–13691. ISSN 0006-2960. PMID 16229458. doi:10.1021/bi050643x. Nobiletin is a nonpeptide compound with a low molecular weight from a citrus fruit and has the activity to rescue bulbectomy-induced memory impairment 

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