印戒细胞
印戒细胞(Signet ring cell)在组织学上是一种恶性的细胞类型,主要见于癌症组织。
![](http://images.weserv.nl/?url=//upload.wikimedia.org/wikipedia/commons/thumb/2/23/Signet_ring_cells_5.jpg/220px-Signet_ring_cells_5.jpg)
![](http://images.weserv.nl/?url=//upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gastric_signet_ring_cell_carcinoma_histopatholgy_%282%29_PAS_stain.jpg/220px-Gastric_signet_ring_cell_carcinoma_histopatholgy_%282%29_PAS_stain.jpg)
![](http://images.weserv.nl/?url=//upload.wikimedia.org/wikipedia/commons/thumb/1/11/Gastric_signet_ring_cell_carcinoma_histopatholgy_%281%29.jpg/220px-Gastric_signet_ring_cell_carcinoma_histopatholgy_%281%29.jpg)
印戒细胞最常见于胃癌[1],但它也可出现在人体的任何组织,包括前列腺[2]、膀胱、胆囊[3]、乳腺、结肠[4]、卵巢间质和睾丸[5]等。
外观
印戒细胞这个名称来源于细胞的外观。印戒细胞含有大量的粘蛋白,从而将细胞核挤向了细胞的一侧外围,类似图章戒指,故得名。
诊断意义
分类
参考资料
- ^ Cancer Research UK. Signet Ring Cancer. cancerhelp.org.uk. URL: http://www.cancerhelp.org.uk/help/default.asp?page=7581 (页面存档备份,存于互联网档案馆). Accessed on: November 2, 2007.
- ^ Leong FJ, Leong AS, Swift J. Signet-ring carcinoma of the prostate. Pathol. Res. Pract. 1996, 192 (12): 1232–8; discussion 1239–41. PMID 9182294.
- ^ Jain V, Gupta K, Kudva R, Rodrigues GS. A case of ovarian metastasis of gallbladder carcinoma simulating primary ovarian neoplasm: diagnostic pitfalls and review of literature. Int. J. Gynecol. Cancer. 2006,. 16 Suppl 1: 319–21. PMID 16515613. doi:10.1111/j.1525-1438.2006.00335.x.
- ^ Makino T, Tsujinaka T, Mishima H; et al. Primary signet-ring cell carcinoma of the colon and rectum: report of eight cases and review of 154 Japanese cases. Hepatogastroenterology. 2006, 53 (72): 845–9. PMID 17153438.
- ^ Michal M, Hes O, Kazakov DV. Primary signet-ring stromal tumor of the testis. Virchows Arch. 2005, 447 (1): 107–10. PMID 15909171. doi:10.1007/s00428-005-1218-2.
- ^ Lee WS, Chun HK, Lee WY; et al. Treatment outcomes in patients with signet ring cell carcinoma of the colorectum. Am. J. Surg. 2007, 194 (3): 294–8. PMID 17693269. doi:10.1016/j.amjsurg.2006.12.041.
- ^ Cabebe EC, Mehta VK, Fisher G. Gastric Cancer. eMedicine.com. URL: http://www.emedicine.com/med/topic845.htm (页面存档备份,存于互联网档案馆). Accessed on: November 8, 2007.
- ^ Tian MM, Zhao AL, Li ZW, Li JY. Phenotypic classification of gastric signet ring cell carcinoma and its relationship with clinicopathologic parameters and prognosis. World J. Gastroenterol. 2007, 13 (23): 3189–98. PMID 17589897.
外部链接
- Signet ring cells - med.Utah.edu.
- Pictures of a signet ring - engravingart.com.
- Signet ring cell definition - cancer.gov.