α,α-二氟甲苯
α,α-二氟甲苯是一种有机化合物,化学式为C7H6F2,它是二氟甲苯的同分异构体之一。它可由苯基溴化镁和二氟碘甲烷在镍配合物的催化下反应制得。[2]它和N-氯代丁二酰亚胺反应,可以得到α,α,α-二氟氯甲苯;和N-溴代丁二酰亚胺反应,得到α,α,α-二氟溴甲苯。[3]
Α,α-二氟甲苯 | |
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识别 | |
CAS号 | 455-31-2 ![]() |
SMILES |
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性质 | |
化学式 | C7H6F2 |
摩尔质量 | 128.12 g·mol−1 |
沸点 | 135 °C(408 K)[1] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ John Bailey, Raymond G. Plevey, John Colin Tatlow. Fluorinations with complex metal fluorides. Part 9. Fluorinations of toluene and xylene derivatives by means of caesium tetrafluorocobaltate [III]. Journal of Fluorine Chemistry. 1987-10, 37 (1): 1–14 [2021-11-09]. doi:10.1016/S0022-1139(00)83080-8. (原始内容存档于2018-06-23) (英语).
- ^ Hirotaka Motohashi, Koichi Mikami. Nickel-Catalyzed Aromatic Cross-Coupling Difluoromethylation of Grignard Reagents with Difluoroiodomethane. Organic Letters. 2018-09-07, 20 (17): 5340–5343 [2021-11-09]. ISSN 1523-7060. doi:10.1021/acs.orglett.8b02264. (原始内容存档于2021-11-09) (英语).
- ^ He, Jinbao; Fittman, Charles U. The Photochemical Synthesis of α,α,α-bromodifluorotoluene and α,α,α-chlorodifluorotoluene. Synthetic Communications (Informa UK Limited). 1999, 29 (5): 855–862. ISSN 0039-7911. doi:10.1080/00397919908086043.