哈爾滿是一種β-咔啉類生物鹼,化學式C12H10N2。它存在於煙草燃燒物中,由色氨酸產生,其含量為0.7~3.6 μg/香煙。[1]它也存在於小果咖啡[2]茶樹[3]等植物中。

哈爾滿
IUPAC名
1-Methyl-9H-pyrido[3,4-b]indole
別名 哈爾滿鹼
識別
CAS號 486-84-0  checkY
PubChem 5281404
ChemSpider 4444755
SMILES
 
  • CC1=NC=CC2=C1NC3=CC=CC=C23
InChI
 
  • 1/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3
InChIKey PSFDQSOCUJVVGF-UHFFFAOYAA
EINECS 207-642-2
ChEBI 5623
KEGG C09209
性質
化學式 C12H10N2
摩爾質量 182.22 g·mol−1
熔點 235—238 °C(508—511 K)
溶解性 Soluble to 10 mM in 1 eq. HCl

methanol: soluble 50 mg/ml

若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ Entry on Harman. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.
  2. ^ Tomas Herraiz, Carolina Chaparro. Human monoamine oxidase enzyme inhibition by coffee and β-carbolines norharman and harman isolated from coffee. Life Sciences. 2006-01, 78 (8): 795–802 [2022-12-27]. doi:10.1016/j.lfs.2005.05.074. (原始內容存檔於2022-10-17) (英語). 
  3. ^ Jiao, Ye; Yan, Yan; He, Zhiyong; Gao, Daming; Qin, Fang; Lu, Mei; Xie, Mingyong; Chen, Jie; Zeng, Maomao. Inhibitory effects of catechins on β-carbolines in tea leaves and chemical model systems. Food & Function. 2018-06-20, 9 (6): 3126–3133 [2022-12-27]. ISSN 2042-650X. PMID 29789822. doi:10.1039/c7fo02053h. (原始內容存檔於2021-10-29).