3-乙硫基丙腈

化合物

3-乙硫基丙腈是一种有机化合物,化学式为C5H9NS,它可由丙烯腈乙硫醇甲醇钠存在下反应得到。[2]它和氨基硫脲加热反应,可以得到5-(2-乙硫基乙基)-1,3,4-噻二唑-2-胺。[3]它可以被氢化铝锂还原为3-乙硫基丙胺。[2]

3-乙硫基丙腈
别名 乙基(氰乙基)硫醚
识别
CAS号 3088-46-8  checkY
性质
化学式 C5H9NS
摩尔质量 115.2 g·mol−1
熔点 49 °C(322 K)[1]
沸点 105—109 °C(378—382 K)(30 torr)[2]
相关物质
相关化学品 3-巯基丙腈
3-甲硫基丙腈
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Butskus, P. F.; Denis, G. I. Cyanoethylation of aromatic amines by acrylonitrile and β-substituted propionitriles. Nauchnye Doklady Vysshei Shkoly, Khimiya i Khimicheskaya Tekhnologiya, 1958: 743-745. ISSN 0470-469X. CODEN NDVSAJ.
  2. ^ 2.0 2.1 2.2 Richard Göschke, Stefan Stutz, Vittorio Rasetti, Nissim-Claude Cohen, Joseph Rahuel, Pascal Rigollier, Hans-Peter Baum, Peter Forgiarini, Christian R. Schnell, Trixie Wagner, Markus G. Gruetter, Walter Fuhrer, Walter Schilling, Frédéric Cumin, Jeanette M. Wood, Jürgen Maibaum. Novel 2,7-Dialkyl-Substituted 5( S )-Amino-4( S )-hydroxy-8-phenyl-octanecarboxamide Transition State Peptidomimetics Are Potent and Orally Active Inhibitors of Human Renin. Journal of Medicinal Chemistry. 2007-10-01, 50 (20): 4818–4831 [2022-07-26]. ISSN 0022-2623. doi:10.1021/jm070314y. (原始内容存档于2022-07-26) (英语). 
  3. ^ M. A. Kukaniev, M. D. Osimov, Z. G. Sangov, S. S. Safarov, M. B. Karimov, T. R. Radjabov. Polyfunctional nitriles in the synthesis of derivatives of 1,3,4-thiadiazolo-[3,2-a]pyrimidines. Chemistry of Heterocyclic Compounds. 2008-07, 44 (7): 882–885 [2022-07-26]. ISSN 0009-3122. doi:10.1007/s10593-008-0125-2 (英语).